Researchers have discovered a key process by which new genes from non-protein coding DNA undergoes mutations to enable export from the nucleus into the cellular cytoplasm where the new gene can be translated into novel polypeptides. In the new study the researchers have shown that far from being accessories, new gene products are often integral in key phenotype characteristics, such as larger brains in human-specific de novo genes from non-protein coding DNA. But before such genes can become novel protein products, they must change to escape the nuclear localization fated for long non-coding RNA sequences: the study elucidates the mutations involved in enabling nuclear export where the new gene can access the translational machinery of the ribosome, and demonstrates via knock-out and overexpression experiments the functional role of novo genes from non-protein coding DNA in organism development, like the enlargement of the cerebral cortex in humans.  

By: William Brown,...

By: William Brown, Biophysicist at the Resonance Science Foundation

In our study The Unified Spacememory Network: from cosmogenesis to consciousness, we described how quantum information processing pathways in the molecular genetic system of the biological organism order permutations in a non-random fashion that result in natural directional adaptation and evolution. Information exchanges involving quantum mechanisms at the molecular level of the biological system with the environment and the entanglement nexus of the Spacememory morphogenic field give a kind of natural intelligence to the evolvability of organisms, allowing for meaningful adaptations to occur at an accelerated rate beyond what would be possible under purely random genetic mutations. As the evolutionary biologist Andreas Wagner states, “natural selection can preserve innovations, but it cannot create them… nature’s many innovations, some uncannily perfect, call for natural principles that...