In search of a cure against cancer patient voice Bonnie J. Addario called out at Forbes for a new paradigm called Transformational Medicine. It is about the Information flow in academic and pharmaceutical efforts to find cures. Currently, the standard of “translational medicine” has a one way information flow in exchange for individual-data, she states. The Addario Lung Cancer Foundation, launched one of the first patient-driven, advocacy campaigns in lung cancer research. “Patients should be driving the research together with pharmaceutical companies and academia, because the cure lies with the patient” says the board member of the Personalized Medicine Coalition.
Instead of one-way flow of information, we can institute Transformational Medicine, where all parties collaborate. The patient is involved at the beginning in clinical trial design, and the information...
A new groundbreaking discovery has been made within the most basic of resources. Scientists have just discovered what they have called “The Discovery of The Millennium”, and a huge revelation in human consciousness.
Scientists from Germany now believe that water has a memory, meaning that what once was seen as a simple commodity has now been closely examined to reveal a scientific revelation, uncovering a mind-blowing truth.
By examining individual drops of water at an incredibly high magnification, scientists were able to physically see that each droplet of water has its own individual microscopic pattern, each distinguishable from the next and uniquely beautiful.
A scientific experiment was carried out whereby a group of students were all encouraged to obtain one drop of water from the same body of water, all at the same time. Through close examination of the individual droplets, it was seen that each produced...
That the human brain contains magnetite is well established; however, its spatial distribution in the brain has remained unknown. A new study shows that the reproducible magnetization patterns of magnetite is preferentially partitioned in the human brain, specifically in the cerebellum and brain stem.
In 1992 researchers identified the presence of magnetite—a permanently magnetic form of iron oxide—in human brain tissue. Iron in the body was no surprise. It is commonly found in ferritin, an intracellular protein common to several organisms, and the magnetite was thought to have formed biogenically, with some possibly originating in ferritin. But the presence of magnetite in the brain could be more than incidental. Various studies have shown that brain cells respond to external magnetic fields. There’s also a disturbing link to neurodegenerative disease: Evidence exists of elevated levels...
How the three domains of life (Archaea, Bacteria and Eukarya) evolved is still a matter of debate. One hypothesis, namely the domain cell theory (DCT), proposes that each of the three domains of life arose from a pre-existing ancestor. In this scenario each domain represents a unique and independent cellular lineage. Another hypothesis posits that Eukarya arose by a cellular fusion event between a bacterium and an archaeon. In their article published in BioEssays, James Staley and Gustavo Caetano-Anollés challenge this popular cell fusion hypothesis. Instead they propose an Archaea-first model and discuss evidence supporting the co-evolution of early archaeal lineages with emerging Bacteria and Eukarya.
Imaging Tool Flags New Proteins, Lipids and DNA to Track Metabolic Changes in Animals
Imaging tools like X-rays and MRI have revolutionized medicine by giving doctors a close up view of the brain and other vital organs in living, breathing people. Now, Columbia University researchers report a new way to zoom in at the tiniest scales to track changes within individual cells.
Described in Nature Communications, the tool combines a widely used chemical tracer, D2O, or heavy water, with a relatively new laser-imaging method called stimulated Raman scattering (SRS). The technique’s potential applications include helping surgeons quickly and precisely remove tumors, to helping to detect head injuries and developmental and metabolic disorders.
“We can use this technology to visualize metabolic activities in a wide range of animals,” said the study’s senior author Wei Min, a chemistry...
On Halloween in 1832, the naturalist Charles Darwin was onboard the HMS Beagle. He marveled at spiders that had landed on the ship after floating across huge ocean distances. “I caught some of the Aeronaut spiders which must have come at least 60 miles,” he noted in his diary. “How inexplicable is the cause which induces these small insects, as it now appears in both hemispheres, to undertake their aerial excursions.”
Small spiders achieve flight by aiming their butts at the sky and releasing tendrils of silk to generate lift. Darwin thought that electricity might be involved when he noticed that spider silk stands seemed to repel each other with electrostatic force, but many scientists assumed that the arachnids, known as “ballooning” spiders, were simply sailing on the wind like a paraglider. The wind power explanation has thus far been unable to account for observations of spiders rapidly launching into the...
Scientists have isolated the two different forms of water molecule for the first time.
Water molecules were known to exist as two distinct "isomers", or types, based on their slightly different properties at the atomic level.
By separating out the two isomers, researchers were able to show that they behave differently in the way that they undergo chemical reactions.
The work appears in Nature Communications.
In basic terms, water molecules consist of a single oxygen atom bonded to a pair of hydrogen atoms (HO).
However, they can be further subdivided based on a property of the nuclei at the hearts of the hydrogen atoms - their "spin".
While they aren't spinning in the sense we would understand, this property of hydrogen nuclei does affect the rotation of the water molecules themselves.
If the nuclear spins of the two hydrogen atoms in water are oriented in the same direction, it is called ortho-water. If they are arranged in different directions, it is known as para-water.
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One of the biggest helpers in our bodies' ongoing efforts to prevent DNA mutations—mutations that can lead to cancer—is actually rather tiny. Electrons, as it turns out, can signal certain proteins to patch up DNA damage. More specifically, the movement of electrons through DNA, traveling between repair proteins bound to the double helix, helps our cells scan for mistakes that regularly arise in our DNA.
Known as DNA charge transport, this biochemical process was first discovered in the early 1990s by Caltech's Jacqueline Barton, the John G. Kirkwood and Arthur A. Noyes Professor of Chemistry, through chemistry experiments using synthetic DNA. Her research group then found evidence that this charge transport chemistry might be utilized by DNA repair proteins in bacteria. Now, a new study shows that DNA charge transport is also at work in human versions of DNA repair...
The properties of water have fascinated scientists for...
The mystery behind how birds navigate might finally be solved: it's not the iron in their beaks providing a magnetic compass, but a newly discovered protein in their eyes that lets them "see" Earth's magnetic fields.
These findings come courtesy of two new papers - one studying robins, the other zebra finches.
The fancy eye protein is called Cry4, and it's part of a class of proteins called cryptochromes - photoreceptors sensitive to blue light, found in both plants and animals. These proteins play a role in regulating circadian rhythms.
There's also been evidence in recent years that, in birds, the cryptochromes in their eyes are responsible for their ability to orient themselves by detecting magnetic fields, a sense called magnetoreception.
We know that birds can only sense magnetic fields if certain wavelengths of light are available - specifically, studies have...
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